Dermoscopy of Post Kala-Azar Dermal Leishmaniasis
نویسندگان
چکیده
© 2018 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Post Kala‐azar dermal leishmaniasis (PKDL) is a late cutaneous manifestation of untreated or partially treated visceral leishmaniasis (VL) and is caused by the same organism, i.e., Leishmania donovani. It characteristically manifests as macules, nodules, plaques, and facial erythema. A 19‐year‐old male presented with erythematous fleshy papules confined to the chin [Figure 1], along with hypopigmented macules involving the trunk and lower limbs. On evaluation, the patient revealed a history of Kala‐azar 1.5 years back with RK‐39 test positivity for the patient. Dermoscopy of the erythematous papule from the chin was performed using Dermlite II hybrid m dermatoscope at 10 × magnification in polarized mode and photographs were captured, which revealed multiple yellow tears and erythema [Figure 2]. Histopathology confirmed the diagnosis of PKDL [Figure 3].
منابع مشابه
DNA polymorphism assay distinguishes isolates of Leishmania donovani that cause kala-azar from those that cause post-kala-azar dermal Leishmaniasis in humans.
Leishmania donovani in India causes visceral infection (kala-azar) and dermal infection (post-kala-azar dermal leishmaniasis). We report here the identification of polymorphism in a well-defined genetic locus among the Leishmania parasites causing the visceral and dermal manifestations, in a comparison of 15 post-kala-azar dermal leishmaniasis and 12 kala-azar patient isolates.
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We assessed the prevalence of post-kala-azar dermal leishmaniasis (PKDL), a late cutaneous manifestation of visceral leishmaniasis (VL), in 16 VL-endemic communities in Bihar, India. The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the post-kala-azar dermal leishmaniasis cases are discussed.
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